Diversity Arrays: a solid state technology for sequence information independent genotyping

Here we present the successful application of the microarray technology platform to the analysis of DNA polymorphisms. Using the rice genome as a model, we demonstrate the potential of a high-throughput genome analysis method called Diversity Arrays Technology, DArT. In the format presented here the technology is assaying for the presence (or amount) of specific DNA fragment in a representation derived from the total genomic DNA of an organism or a population of organisms.